Quinolone-isoniazid hybrids: Synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation

Published: 12/01/2019
Quinolone-isoniazid hybrids: Synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation
Source: FEEDS.RSC.ORG

Med. Chem. Commun. , 2019, Accepted Manuscript DOI : 10.1039/C8MD00480C, Research Article Richard M. Beteck, Ronnett Seldon, Audrey Jordaan, Digby Warner, Heinrich C Hoppe, Dustin Laming, Lesetja J. Legoabe, Setshaba Khanye Herein, we propose novel quinolones incorporating an INH moiety as potential drug templates against TB. The quinolone-based compounds bearing an INH moiety attached via a hydra

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