Computational Identification of the Binding Mechanism of Triple Reputake Inhibitor Amitifadine for the Treatment of Major Depressive Disorder

Published: 1/02/2018
Computational Identification of the Binding Mechanism of Triple Reputake Inhibitor Amitifadine for the Treatment of Major Depressive Disorder
Source: FEEDS.RSC.ORG

Phys. Chem. Chem. Phys. , 2018, Accepted Manuscript DOI : 10.1039/C7CP07869B, Paper Weiwei Xue, Panpan Wang, Gao Tu, Fengyuan Yang, Guoxun Zheng, Xiaofeng Li, Xiaoxu Li, Yuzong Chen, Xiaojun Yao, Feng Zhu Amitifadine, the only drug ever clinically tested in Phase 3 for treating depression, is a triple reuptake inhibitor (TRI) that simultaneously interacts with human monoamine transporters (MATs) i

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