Brain-derived neurotrophic factor derived from sensory neurons plays a critical role in chronic pain

Published: 30/01/2018
Brain-derived neurotrophic factor derived from sensory neurons plays a critical role in chronic pain
Source: ACADEMIC.OUP.COM

Abstract Many studies support the pro-nociceptive role of brain-derived neurotrophin factor (BDNF) in pain processes in the peripheral and central nervous system. We have previously shown that nociceptor-derived BDNF is involved in inflammatory pain. Microglial-derived BDNF has also been shown to be involved in neuropathic pain. However, the distinct contribution of primary afferent-derived BNDF t

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